Publications in relation to Fraunhofer CIMD

Recent Publications

Automated application of low energy electron irradiation enables inactivation of pathogen- and cell-containing liquids in biomedical research and production facilities
Fertey J***, Thoma M**, Beckmann J*, Bayer L***, Finkensieper J***, Reißhauer S***, Berneck BS***, Issmail L***, Schönfelder J*, Casado JP*, Poremba A*, Rögner F-H*, Standfest B**, Makert GR***, Walcher L***, Kistenmacher A-K***, Fricke S***, Grunwald T***, Ulbert S***
*Fraunhofer FEP, **Fraunhofer IPA, ***Fraunhofer IZI

Sci Rep. 2020 Jul 30; 10(1):12786. doi: 10.1038/s41598-020-69347-7

Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms
Maculins T, Garcia-Pardo J*, Skenderovic A, Gebel J, Putyrski M, Vorobyov A*, Busse P, Varga G, Kuzikov M*, Zaliani A*, Rahighi S, Schaeffer V, Parnham MJ*, Sidhu SS, Ernst A, Dötsch V, Akutsu M, Dikic I*
*Fraunhofer IME

Cell Chem Biol. 2020 Jul 27;S2451-9456(20)30283-X. doi: 10.1016/j.chembiol.2020.07.010

From Cancer to Immune-Mediated Diseases and Tolerance Induction: Lessons Learned From Immune Oncology and Classical Anti-cancer Treatment
Klöß S**, Dehmel S***, Braun A***, Parnham MJ*, Köhl U**, Schiffmann S*
*Fraunhofer IME, **Fraunhofer IZI; ***Fraunhofer ITEM

Front Immunol. 2020 Jul 08; 11:1423. doi: 10.3389/fimmu.2020.01423

Intravenous Bone Marrow Mononuclear Cells Transplantation in Aged Mice Increases Transcription of Glucose Transporter 1 and Na+/K+-ATPase at Hippocampus Followed by Restored Neurological Functions
Takeuchi Y, Okinaka Y, Yuko Ogawa, Kikuchi-Taura A, Kataoka Y, Gul S*, Claussen C*, Boltze J, Taguchi A
*Fraunhofer IME

Front Aging Neurosci. 2020 Jun 11;12:170. doi: 10.3389/fnagi.2020.00170

Natural antiviral compound silvestrol modulates human monocyte‐derived macrophages and dendritic cells
Blum L*, Geisslinger G*, Parnham MJ*, Grünweller A, Schiffmann S*
*Fraunhofer IME

J Cell Mol Med. 2020 Jun; 24(12):6988–99. doi: 10.1111/jcmm.15360 . Epub 2020 May 6.

Secukinumab versus adalimumab for treatment of active psoriatic arthritis (EXCEED): a double-blind, parallel-group, randomised, active-controlled, phase 3b trial
McInnes IB, Behrens F*, Mease PJ, Kavanaugh A, Ritchlin C, Nash P, Masmitja JG, Goupille P, Korotaeva T, Gottlieb AB, Martin R, Ding K, Pellet P, Mpofu S, Pricop L, EXCEED Study Group
*Fraunhofer IME

Lancet. 2020 May 09; 395(10235):1496-1505. doi: 10.1016/S0140-6736(20)30564-X

Extracellular vesicle (ECV)-modified polyethylenimine (PEI) complexes for enhanced siRNA delivery in vitro and in vivo
Zhupanyn P, Ewe A, Büch T, Malek A, Rademacher P, Müller C*, Reinert A, Jaimes Y*, Aigner A
*Fraunhofer IZI

J Control Release. 2020 Mar 10; 319:63-76.  doi: 10.1016/j.jconrel.2019.12.032

Tumors Provoke Inflammation and Perineural Microlesions at Adjacent Peripheral Nerves
Cohnen J, Kornstädt L, Hahnefeld L*, Ferreiros N*, Pierre S, Köhl U**, Deller T, Geisslinger G*, Scholich K*
*Fraunhofer IME, **Fraunhofer IZI

Cells. 2020 Jan 29; 9(2):320. doi: 10.3390/cells9020320

4 Ds in health research—working together toward rapid precision medicine
Niederberger E, Parnham MJ*, Maas J, Geisslinger G*.
*Fraunhofer IME, Fraunhofer CIMD
EMBO Mol Med., 2019 Sep 18:e10917. doi: 10.15252/emmm.201910917

Novel Approaches to Persistent Pain Therapy
Sisignano M, Parnham MJ*, Geisslinger G*.
*Fraunhofer IME
Trends Pharmacol Sci. 2019 Jun;40(6):367-377. doi: 10.1016/ . Epub 2019 May 8.

The Epitope-specific anti-Human CD4 Antibody MAX.16H5 and its Role in Immune Tolerance
Stahl L*, Duenkel A*, Hilger N, Tretbar US*, Fricke S*
*Fraunhofer IZI
Front Immunol. 2019 May 24;10:1035. doi: 10.3389/fimmu.2019.01035 . eCollection 2019.

Potential biomarkers for persistent and neuropathic pain therapy
Sisignano M, Lötsch J, Parnham MJ*, Geisslinger G*.
*Fraunhofer IME

Pharmacol Ther. 2019 Jul;199:16-29. doi: 10.1016/j.pharmthera.2019.02.004 . Epub 2019 Feb 10.

CAR-Expressing Natural Killer Cells for Cancer Retargeting
Kloess S*, Kretschmer A*, Stahl L*, Fricke S*, Koehl U*.
*Fraunhofer IZI
Transfus Med Hemother. 2019 Feb;46(1):4-13. doi: 10.1159/000495771 . Epub 2019 Feb 5.

Non-human papillomaviruses for gene delivery in vitro and in vivo
Bayer L*, Gümpel J*, Hause G, Müller M, Grunwald T*
*Fraunhofer IZI
PLoS One. 2018 Jun 18;13(6):e0198996. doi: 10.1371/journal.pone.0198996 . eCollection 2018.